Download e-book for kindle: Theory of Heart: Biomechanics, Biophysics, and Nonlinear by Bruce Smaill, Peter Hunter (auth.), Leon Glass, Peter

By Bruce Smaill, Peter Hunter (auth.), Leon Glass, Peter Hunter, Andrew McCulloch (eds.)

ISBN-10: 1461231183

ISBN-13: 9781461231189

ISBN-10: 1461278031

ISBN-13: 9781461278030

In fresh years there was a development in curiosity in learning the guts from the viewpoint of the actual sciences: mechanics, fluid move, electromechanics. This quantity is the results of a workshop held in July 1989 on the Institute for Nonlinear Sciences on the college of California at San Diego that introduced jointly scientists and clinicians with graduate scholars and postdoctoral fellows who shared an curiosity within the center. The chapters have been ready by means of the invited audio system as didactic reports in their matters but additionally contain the constitution, mechanical houses, and serve as of the guts and the myocardium, electric task of the center and myocardium, and mathematical types of center function.

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Additional resources for Theory of Heart: Biomechanics, Biophysics, and Nonlinear Dynamics of Cardiac Function

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Thin myocardial sections were sliced from the right and left ventricular free walls at various transmural depths using a dermatome. Specimens 25-mm square cut from the slices were oriented so that one pair of sides was parallel to the myocardial fiber direction. 0-mm central square. The specimen was then mounted in the biaxial testing apparatus. Testing was carried out at approximately lOoC in an oxygenated Krebs-Henseleit solution to which 1 mM EGTA had been added. Samples were subjected to 10 cycles of equibiaxial or uniaxial force loading at three different loading rates.

Maximum fiber extensions ranged between 15 and 25% and all specimens were highly compliant in the cross-fiber direction, although "strain-locking" was seen at extensions of 60 to 80%. Observation of the surface of a typical sample at high magnification suggests that cross-fiber strains are associated with the elastic deformation of muscle fiber bundles up to 140 I'm across, together with a partly reversible rearrangement of these fiber bundles. 5, comparable results are given for a set of midmyocardial specimens under uniaxial load.

H. M. Factor. Coileq. perimysial fibres in papillary muscle in rat heart: Morphology, distribution and changes in configuration. Cire. , 63:577-592, 1988. [39] S. Sato, M. W. Millard, H. Fujiwara, and A. Schwartz. Connective tissue changes in early ischaemia of porcine myocardium: An ultrastructure study. J. Mol. Cell. , 15:261-267, 1983. J. Shacklock. Biaxial Testing of Cardiac Tissue. Master's thesis, University of Auckland, New Zealand, 1987. D. Streeter. Gross morphology and fiber geometry of the heart.

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Theory of Heart: Biomechanics, Biophysics, and Nonlinear Dynamics of Cardiac Function by Bruce Smaill, Peter Hunter (auth.), Leon Glass, Peter Hunter, Andrew McCulloch (eds.)

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