By Franco M. Muggia (auth.), Andrea Bonetti, Roberto Leone, Franco M. Muggia, Stephen B. Howell (eds.)
The platinum-containing chemotherapeutic brokers stay key elements of some of the most desirable regimens for the therapy of melanoma. New information regarding the chemistry, pharmacology and molecular mechanisms through which those medicines paintings is resulting in either the improvement of latest medicines and more suitable use of current individuals of this type. greater definition of the genetic foundation of malignancies is supplying exciting new insights in to find out how to use those medicines in a extra individualized demeanour. "Platinum and different Heavy steel Compounds in melanoma Chemotherapy: Molecular Mechanisms and medical Applications", edited through Andrea Bonetti, Steve B. Howell, Roberto Leone, and Franco Muggia, presents succinct summaries of the foremost new advancements in box of platinum drug treatment drawn from displays made on the 10th International Symposium on Platinum Coordination Compounds in melanoma Chemotherapy that came about in Verona, Italy, in December 2007. This assembly, held as soon as each four years, introduced jointly the world’s prime investigators engaged on platinum medicinal drugs and their contributions supply an in depth survey of the foremost learn instructions during this speedily evolving field.
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Extra resources for Platinum and Other Heavy Metal Compounds in Cancer Chemotherapy: Molecular Mechanisms and Clinical Applications
Systemic and tumor disposition of platinum after administration of cisplatin or STEALTH liposomal-cisplatin formulations (SPI-077 and SPI-077 B103) in a preclinical tumor model of melanoma. Cancer Chemother Pharmacol 2004;53:329–36. Stathopoulos GP, Boulikas T, Vougiouka M, et al. Pharmacokinetics and adverse reactions of a new liposomal cisplatin (lipoplatin): phase I study. Oncol Rep 2005;13:589–95. Stathopoulos GP, Boulikas T, Kourvetaris A, Stathopoulos J. Liposomal oxaliplatin in the treatment of advanced cancer: a phase I study.
Nicolini M. Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy. Boston, US: Martinus Nihjoff, 1988. 35. Howell SB. Platinum and other metal coordination compounds in cancer chemotherapy. New York, US: Plenum, 1991. 36. Pinedo HM, Schornagel JH. Platinum and other metal coordination compounds in cancer chemotherapy. New York, US: Plenum, 1996. 37. Kelland LR, Farrell NP. Platinum-based drugs in cancer therapy. Totowa, NJ, US: Humana, 2000. Studies on New Platinum Compounds Fazlul Huq, Jun Qing Yu, and Philip Beale Abstract This chapter provides a review of the activities of a number of recently synthesized planaramineplatinum(II) complexes and platinum compounds with multiple metal centers against human ovarian cancer cell lines.
J Liposome Res 2002;12:1–3. Dragovich T, Mendelson D, Kurtin S, Richardson K, Von Hoff D, Hoos A. A phase 2 trial of the liposomal DACH platinum L-NDDP in patients with therapy-refractory advanced colorectal cancer. Cancer Chemother Pharmacol 2006;58:759–64. Burger KN, Staffhorst RW, de Vijlder HC, et al. Nanocapsules: lipid-coated aggregates of cisplatin with high cytotoxicity. Nat Med 2002;8:81–4. Chupin V, de Kroon AI, de Kruijff B. Molecular architecture of nanocapsules, bilayerenclosed solid particles of cisplatin.
Platinum and Other Heavy Metal Compounds in Cancer Chemotherapy: Molecular Mechanisms and Clinical Applications by Franco M. Muggia (auth.), Andrea Bonetti, Roberto Leone, Franco M. Muggia, Stephen B. Howell (eds.)