By Wolfgang Drexler, James G. Fujimoto
Optical coherence tomography (OCT) is the optical analog of ultrasound imaging and is a strong imaging method that permits non-invasive, in vivo, excessive answer, cross-sectional imaging in organic tissue. Between 30 to forty Million OCT imaging systems are played according to 12 months in ophthalmology. The total industry is predicted at greater than 1/2 Billion USD.
A new iteration OCT technology was constructed, dramatically expanding solution and pace, attaining in vivo optical biopsy, i.e. the visualization of tissue architectural morphology in situ and in genuine time. sensible extensions of OCT know-how let non-invasive, intensity resolved practical review and imaging of tissue.
The e-book introduces OCT expertise and purposes not just from an optical and technological standpoint, but in addition from the biomedical and medical perspective. This moment version is broadly prolonged and covers significantly more topics then the 1st variation of this booklet. The chapters are written by leading overseas learn teams, in a method understandable to a extensive viewers. it is going to be of curiosity not just to physicists, scientists and engineers, but in addition to biomedical and scientific researchers from varied scientific specialties
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Additional resources for Optical Coherence Tomography: Technology and Applications 3 Volume Set
The speed of sound is $1,500 m/s, while the speed of light is approximately 3 Â 108 m/s. In order to measure distances with a 100 mm resolution, a typical resolution for ultrasound imaging, a time resolution of $100 ns is required. This resolution is well within the limits of electronic detection. Ultrasound technology has advanced significantly in recent years with the availability of high-performance, low-cost analog to digital converters and digital signal processing technology. Unlike sound, the detection of light echoes requires much higher time resolution.
The echo magnitude versus delay or axial scan is obtained by demodulating the interference signal. (right) Measurement of the anterior chamber in an ex vivo bovine eye. A 10 mm axial resolution was achieved using a low-coherence diode light source at $800 nm. Interferometry enables high sensitivity detection of optical echoes and is the basis for optical coherence tomography (From Huang et al. ) Interferometry techniques perform correlation measurements by interfering light that is backscattered from the tissue with light that has traveled through a reference path with a known time delay.
Although the imaging depth of OCT is limited by attenuation from light scattering, OCT can be integrated with many medical devices such as catheters, endoscopes, laparoscopes, or needles, to access luminal organ systems such as the GI tract and airway as well as solid organs and masses. OCT has become a standard of care in clinical ophthalmology and promises to have a powerful impact on many medical applications ranging from intravascular imaging to the assessment of neoplasia and guidance of minimally invasive surgical procedures.
Optical Coherence Tomography: Technology and Applications 3 Volume Set by Wolfgang Drexler, James G. Fujimoto